I do use Chrome, and I love Chrome. The sites that don't support Chrome are usually sloppy code anyhow (CHRYSLER!!!) and don't work in any browser well!
Here's my list. I use the Beta version of Chrome so it has the ability to use profiles (about time). This comes in VERY handy for me. Chrome is also extremely fast compared to IE. It does take a lot of ram and I do keep a lot of extensions running with a lot of windows open.
My Extensions:
Adblock Plus for Google Chrome (Beta) - easy to add filters with a click to block ads / elements
Better Gmail - because I use gmail for all my email
Docs PDF/PowerPoint Viewer (by Google) - because I use Google Docs.
GoMBoX - preview google images in a cool image popup (lightbox)
Google Voice - because I use Google Voice - if you use, it's a must.
IE Tab - allows you to switch to the iexplore engine for sites like CHRYSLER
Publish sync for google+ & facebook - when posting to FB, also posts to twitter, G+ and supports videos, images & web-links
Stylish - Car-Research is one of those unsupported sites. With stylish, you can add code to change how a page looks. I used this to fix the blue/yellow bar in car-research. Inserts CSS on the fly.
Unsubscribe.com - decent tool. Worth checking out.
One handy feature is the "developer tools" feature (which i'm sure FF has) which make it easy to troubleshoot code on a website you may or may not be coding! Additionally, Chrome has a built-in sync feature for your bookmarks, extensions, etc. Lastly, it has a spell check while you type.
I can live with some of the issues some sites have with not supporting Chrome because it just works that much better for me than IE.